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Fighting Against Promoter DNA Hyper-Methylation: Protective Histone Modification Profiles of Stress-Resistant Intestinal Stem Cells

Aberrant DNA methylation in stem cells is a hallmark of aging and tumor development. Recently, we have suggested that promoter DNA hyper-methylation originates in DNA repair and that even successful DNA repair might confer this kind of epigenetic long-term change. Here, we ask for interrelations bet...

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Detalles Bibliográficos
Autores principales: Thalheim, Torsten, Hopp, Lydia, Herberg, Maria, Siebert, Susann, Kerner, Christiane, Quaas, Marianne, Schweiger, Michal R., Aust, Gabriela, Galle, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139626/
https://www.ncbi.nlm.nih.gov/pubmed/32178409
http://dx.doi.org/10.3390/ijms21061941