Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment

Manipulating autophagy is a promising strategy for treating cancer as several autophagy inhibitors are shown to induce autophagic cell death. One of these, autophagonizer (APZ), induces apoptosis-independent cell death by binding an unknown target via an unknown mechanism. To identify APZ targets, w...

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Detalles Bibliográficos
Autores principales: Hwang, Hui-Yun, Cho, Yoon Sun, Kim, Jin Young, Yun, Ki Na, Yoo, Jong Shin, Lee, Eunhyeong, Kim, Injune, Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139627/
https://www.ncbi.nlm.nih.gov/pubmed/32120820
http://dx.doi.org/10.3390/cancers12030543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139627/
https://www.ncbi.nlm.nih.gov/pubmed/32120820
http://dx.doi.org/10.3390/cancers12030543

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