The Landscape of the Anti-Kinase Activity of the IDH1 Inhibitors

Isocitrate dehydrogenases constitute a class of enzymes that are crucial for cellular metabolism. The overexpression or mutation of isocitrate dehydrogenases are often found in leukemias, glioblastomas, lung cancers, and ductal pancreatic cancer among others. Mutation R132H, which changes the functi...

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Detalles Bibliográficos
Autores principales: Malarz, Katarzyna, Mularski, Jacek, Pacholczyk, Marcin, Musiol, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139656/
https://www.ncbi.nlm.nih.gov/pubmed/32110969
http://dx.doi.org/10.3390/cancers12030536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139656/
https://www.ncbi.nlm.nih.gov/pubmed/32110969
http://dx.doi.org/10.3390/cancers12030536

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