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Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation

The induction of heat shock response in the macula has been proposed as a useful therapeutic strategy for retinal neurodegenerative diseases by promoting proteostasis and enhancing protective chaperone mechanisms. We applied transpupillary 1064 nm long-duration laser heating to the mouse (C57Bl/6J)...

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Detalles Bibliográficos
Autores principales: Amirkavei, Mooud, Pitkänen, Marja, Kaikkonen, Ossi, Kaarniranta, Kai, André, Helder, Koskelainen, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139698/
https://www.ncbi.nlm.nih.gov/pubmed/32192227
http://dx.doi.org/10.3390/ijms21062063