Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

DNA glycosylases are emerging as relevant pharmacological targets in inflammation, cancer and neurodegenerative diseases. Consequently, the search for inhibitors of these enzymes has become a very active research field. As a continuation of previous work that showed that 2-thioxanthine (2TX) is an i...

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Detalles Bibliográficos
Autores principales: Rieux, Charlotte, Goffinont, Stéphane, Coste, Franck, Tber, Zahira, Cros, Julien, Roy, Vincent, Guérin, Martine, Gaudon, Virginie, Bourg, Stéphane, Biela, Artur, Aucagne, Vincent, Agrofoglio, Luigi, Garnier, Norbert, Castaing, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139703/
https://www.ncbi.nlm.nih.gov/pubmed/32192183
http://dx.doi.org/10.3390/ijms21062058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139703/
https://www.ncbi.nlm.nih.gov/pubmed/32192183
http://dx.doi.org/10.3390/ijms21062058

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