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Inhibitory Effect and Mechanism of Action of Quercetin and Quercetin Diels-Alder anti-Dimer on Erastin-Induced Ferroptosis in Bone Marrow-Derived Mesenchymal Stem Cells

In this study, the anti-ferroptosis effects of catecholic flavonol quercetin and its metabolite quercetin Diels-Alder anti-dimer (QDAD) were studied using an erastin-treated bone marrow-derived mesenchymal stem cell (bmMSCs) model. Quercetin exhibited higher anti-ferroptosis levels than QDAD, as ind...

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Detalles Bibliográficos
Autores principales: Li, Xican, Zeng, Jingyuan, Liu, Yangping, Liang, Minshi, Liu, Qianru, Li, Zhen, Zhao, Xiaojun, Chen, Dongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139729/
https://www.ncbi.nlm.nih.gov/pubmed/32131401
http://dx.doi.org/10.3390/antiox9030205