Role of Akt Activation in PARP Inhibitor Resistance in Cancer

Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, de novo and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and the underlying mecha...

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Detalles Bibliográficos
Autores principales: Gallyas, Ferenc, Sumegi, Balazs, Szabo, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139751/
https://www.ncbi.nlm.nih.gov/pubmed/32106627
http://dx.doi.org/10.3390/cancers12030532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139751/
https://www.ncbi.nlm.nih.gov/pubmed/32106627
http://dx.doi.org/10.3390/cancers12030532

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