Functional Classification of TP53 Mutations in Acute Myeloid Leukemia

Mutations of the TP53 gene occur in a subset of patients with acute myeloid leukemia (AML) and confer an exceedingly adverse prognosis. However, whether different types of TP53 mutations exert a uniformly poor outcome has not been investigated yet. Here, we addressed this issue by analyzing data of...

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Detalles Bibliográficos
Autores principales: Dutta, Sayantanee, Pregartner, Gudrun, Rücker, Frank G., Heitzer, Ellen, Zebisch, Armin, Bullinger, Lars, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139772/
https://www.ncbi.nlm.nih.gov/pubmed/32164171
http://dx.doi.org/10.3390/cancers12030637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139772/
https://www.ncbi.nlm.nih.gov/pubmed/32164171
http://dx.doi.org/10.3390/cancers12030637

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