Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography

A focused library of newly designed monomeric and dimeric naphthalene diimides (NDIs) was analyzed in its ability to recognize specific G-quadruplex (G4) structures discriminating duplex DNA. The best G4 ligands—according to an affinity chromatography-based screening method named G4-CPG—were tested...

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Detalles Bibliográficos
Autores principales: Platella, Chiara, Pirota, Valentina, Musumeci, Domenica, Rizzi, Federica, Iachettini, Sara, Zizza, Pasquale, Biroccio, Annamaria, Freccero, Mauro, Montesarchio, Daniela, Doria, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139804/
https://www.ncbi.nlm.nih.gov/pubmed/32183038
http://dx.doi.org/10.3390/ijms21061964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139804/
https://www.ncbi.nlm.nih.gov/pubmed/32183038
http://dx.doi.org/10.3390/ijms21061964

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