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Computational Models Using Multiple Machine Learning Algorithms for Predicting Drug Hepatotoxicity with the DILIrank Dataset

Drug-induced liver injury (DILI) remains one of the challenges in the safety profile of both authorized and candidate drugs, and predicting hepatotoxicity from the chemical structure of a substance remains a task worth pursuing. Such an approach is coherent with the current tendency for replacing no...

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Detalles Bibliográficos
Autores principales: Ancuceanu, Robert, Hovanet, Marilena Viorica, Anghel, Adriana Iuliana, Furtunescu, Florentina, Neagu, Monica, Constantin, Carolina, Dinu, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139829/
https://www.ncbi.nlm.nih.gov/pubmed/32204453
http://dx.doi.org/10.3390/ijms21062114