In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma

Uncontrolled MAPK signaling is the main oncogenic driver in metastatic melanomas bearing mutations in BRAF kinase. These tumors are currently treated with the combination of BRAF/MEK inhibitors (MAPKi), but this therapy is plagued by drug resistance. In this context we recently discovered that sever...

Descripción completa

Detalles Bibliográficos
Autores principales: Fattore, Luigi, Campani, Virginia, Ruggiero, Ciro Francesco, Salvati, Valentina, Liguoro, Domenico, Scotti, Lorena, Botti, Gerardo, Ascierto, Paolo Antonio, Mancini, Rita, De Rosa, Giuseppe, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139872/
https://www.ncbi.nlm.nih.gov/pubmed/32178301
http://dx.doi.org/10.3390/ijms21061930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139872/
https://www.ncbi.nlm.nih.gov/pubmed/32178301
http://dx.doi.org/10.3390/ijms21061930

Ejemplares similares