4-Pyridinio-1,4-Dihydropyridines as Calcium Ion Transport Modulators: Antagonist, Agonist, and Dual Action

A set of six new 4-pyridinio-1,4-dihydropyridine (1,4-DHP) compounds has been synthesized. The calcium channel modulating activity of these compounds was evaluated in an aorta vascular smooth muscle cell line (A7R5), in an isolated rat aortic ring model, and in human neuroblastoma cell lines (SH-SY5...

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Detalles Bibliográficos
Autores principales: Domracheva, Ilona, Kanepe-Lapsa, Iveta, Vilskersts, Reinis, Bruvere, Imanta, Bisenieks, Egils, Velena, Astrida, Turovska, Baiba, Duburs, Gunars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139875/
https://www.ncbi.nlm.nih.gov/pubmed/32308799
http://dx.doi.org/10.1155/2020/2075815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139875/
https://www.ncbi.nlm.nih.gov/pubmed/32308799
http://dx.doi.org/10.1155/2020/2075815

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