Glutaminases as a Novel Target for SDHB-Associated Pheochromocytomas/Paragangliomas

Pheochromocytoma/paragangliomas (Pheo/PGL) are rare endocrine cancers with strong genetic background. Mutations in the SDHB subunit of succinate dehydrogenase (SDH) predispose patients to malignant disease with limited therapeutic options and poor prognosis. Using a host of cellular and molecular bi...

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Detalles Bibliográficos
Autores principales: Sarkadi, Balazs, Meszaros, Katalin, Krencz, Ildiko, Canu, Letizia, Krokker, Lilla, Zakarias, Sara, Barna, Gabor, Sebestyen, Anna, Papay, Judit, Hujber, Zoltan, Butz, Henriett, Darvasi, Otto, Igaz, Peter, Doczi, Judit, Luconi, Michaela, Chinopoulos, Christos, Patocs, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139890/
https://www.ncbi.nlm.nih.gov/pubmed/32150977
http://dx.doi.org/10.3390/cancers12030599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139890/
https://www.ncbi.nlm.nih.gov/pubmed/32150977
http://dx.doi.org/10.3390/cancers12030599

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