Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus laevis Oocytes

Oocytes are postulated to repress the proton pumps (e.g., complex IV) and ATP synthase to safeguard mitochondrial DNA homoplasmy by curtailing superoxide production. Whether the ATP synthase is inhibited is, however, unknown. Here we show that: oligomycin sensitive ATP synthase activity is significa...

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Detalles Bibliográficos
Autores principales: Cobley, James, Noble, Anna, Bessell, Rachel, Guille, Matthew, Husi, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139892/
https://www.ncbi.nlm.nih.gov/pubmed/32150908
http://dx.doi.org/10.3390/antiox9030215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139892/
https://www.ncbi.nlm.nih.gov/pubmed/32150908
http://dx.doi.org/10.3390/antiox9030215

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