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Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules

HER3-binding affibody molecules are a promising format for visualization of HER3 expression. Cobalt-55, a positron-emitting isotope, with a half-life of 17.5 h, allows for next-day imaging. We investigated the influence of the charge of the radiocobalt–chelator complex on the biodistribution of anti...

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Detalles Bibliográficos
Autores principales: Rinne, Sara S., Dahlsson Leitao, Charles, Saleh-nihad, Zahra, Mitran, Bogdan, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139902/
https://www.ncbi.nlm.nih.gov/pubmed/32183096
http://dx.doi.org/10.3390/ijms21061972