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Benefits of Combined All-Trans Retinoic Acid and Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia Cells and Further Enhancement by Inhibition of Atypically Expressed Transglutaminase 2

Randomized trials in acute promyelocytic leukemia patients have shown that treatment with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) is superior in efficacy to monotherapy, with significantly decreased mortality. So far, there are little data available to explain the...

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Detalles Bibliográficos
Autores principales: Jambrovics, Károly, Uray, Iván P., Keillor, Jeffrey W., Fésüs, László, Balajthy, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139906/
https://www.ncbi.nlm.nih.gov/pubmed/32168763
http://dx.doi.org/10.3390/cancers12030648