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Modeling the Efficacy of Oncolytic Adenoviruses In Vitro and In Vivo: Current and Future Perspectives

Oncolytic adenoviruses (OAd) selectively target and lyse tumor cells and enhance anti- tumor immune responses. OAds have been used as promising cancer gene therapies for many years and there are a multitude of encouraging pre-clinical studies. However, translating OAd therapies to the clinic has had...

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Detalles Bibliográficos
Autores principales: McKenna, Mary K., Rosewell-Shaw, Amanda, Suzuki, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139921/
https://www.ncbi.nlm.nih.gov/pubmed/32155969
http://dx.doi.org/10.3390/cancers12030619