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Undiscovered Roles for Transthyretin: From a Transporter Protein to a New Therapeutic Target for Alzheimer’s Disease

Transthyretin (TTR), an homotetrameric protein mainly synthesized by the liver and the choroid plexus, and secreted into the blood and the cerebrospinal fluid, respectively, has been specially acknowledged for its functions as a transporter protein of thyroxine and retinol (the latter through bindin...

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Detalles Bibliográficos
Autores principales: Gião, Tiago, Saavedra, Joana, Cotrina, Ellen, Quintana, Jordi, Llop, Jordi, Arsequell, Gemma, Cardoso, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139926/
https://www.ncbi.nlm.nih.gov/pubmed/32197355
http://dx.doi.org/10.3390/ijms21062075