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Targeted Deletion of PTEN in Kisspeptin Cells Results in Brain Region- and Sex-Specific Effects on Kisspeptin Expression and Gonadotropin Release

Kisspeptin-expressing neurons in the anteroventral periventricular nucleus (AVPV) and the arcuate nucleus (ARC) of the hypothalamus relay hormonal and metabolic information to gonadotropin-releasing hormone neurons, which in turn regulate pituitary and gonadal function. Phosphatase and tensin homolo...

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Detalles Bibliográficos
Autores principales: Negrón, Ariel L., Yu, Guiqin, Boehm, Ulrich, Acosta-Martínez, Maricedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139936/
https://www.ncbi.nlm.nih.gov/pubmed/32204355
http://dx.doi.org/10.3390/ijms21062107