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The Role of Sartans in the Treatment of Stroke and Subarachnoid Hemorrhage: A Narrative Review of Preclinical and Clinical Studies

Background: Delayed cerebral vasospasm (DCVS) due to aneurysmal subarachnoid hemorrhage (aSAH) and its sequela, delayed cerebral ischemia (DCI), are associated with poor functional outcome. Endothelin-1 (ET-1) is known to play a major role in mediating cerebral vasoconstriction. Angiotensin-II-type-...

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Detalles Bibliográficos
Autores principales: Wanderer, Stefan, Grüter, Basil E., Strange, Fabio, Sivanrupan, Sivani, Di Santo, Stefano, Widmer, Hans Rudolf, Fandino, Javier, Marbacher, Serge, Andereggen, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139942/
https://www.ncbi.nlm.nih.gov/pubmed/32156050
http://dx.doi.org/10.3390/brainsci10030153