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Extracellular Redox Regulation of α7β Integrin-Mediated Cell Migration Is Signaled via a Dominant Thiol-Switch

While adhering to extracellular matrix (ECM) proteins, such as laminin-111, cells temporarily produce hydrogen peroxide at adhesion sites. To study the redox regulation of α7β1 integrin-mediated cell adhesion to laminin-111, a conserved cysteine pair within the α-subunit hinge region was replaced fo...

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Detalles Bibliográficos
Autores principales: Bergerhausen, Lukas, Grosche, Julius, Meißner, Juliane, Hecker, Christina, Caliandro, Michele F., Westerhausen, Christoph, Kamenac, Andrej, Rezaei, Maryam, Mörgelin, Matthias, Poschmann, Gereon, Vestweber, Dietmar, Hanschmann, Eva-Maria, Eble, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139957/
https://www.ncbi.nlm.nih.gov/pubmed/32164274
http://dx.doi.org/10.3390/antiox9030227