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Ligand Binding Mechanism and Its Relationship with Conformational Changes in Adenine Riboswitch
Riboswitches are naturally occurring RNA aptamers that control the expression of essential bacterial genes by binding to specific small molecules. The binding with both high affinity and specificity induces conformational changes. Thus, riboswitches were proposed as a possible molecular target for d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139962/ https://www.ncbi.nlm.nih.gov/pubmed/32168940 http://dx.doi.org/10.3390/ijms21061926 |