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Ligand Binding Mechanism and Its Relationship with Conformational Changes in Adenine Riboswitch

Riboswitches are naturally occurring RNA aptamers that control the expression of essential bacterial genes by binding to specific small molecules. The binding with both high affinity and specificity induces conformational changes. Thus, riboswitches were proposed as a possible molecular target for d...

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Detalles Bibliográficos
Autores principales: Hu, Guodong, Li, Haiyan, Xu, Shicai, Wang, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139962/
https://www.ncbi.nlm.nih.gov/pubmed/32168940
http://dx.doi.org/10.3390/ijms21061926

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