NUDT7 Loss Promotes Kras(G12D) CRC Development

Studies have suggested that dysregulation of peroxisomal lipid metabolism might play an important role in colorectal cancer (CRC) development. Here, we found that Kras(G12D)-driven CRC tumors demonstrate dysfunctional peroxisomal β-oxidation and identified Nudt7 (peroxisomal coenzyme A diphosphatase...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Park, Sujeong, Oh, Jinjoo, Kim, Deokha, Ryu, Ji Hyun, Park, Won Cheol, Baek, In-Jeoung, Cheng, Xi, Lu, Xin, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139971/
https://www.ncbi.nlm.nih.gov/pubmed/32131398
http://dx.doi.org/10.3390/cancers12030576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139971/
https://www.ncbi.nlm.nih.gov/pubmed/32131398
http://dx.doi.org/10.3390/cancers12030576

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