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KLF5 Is Crucial for Androgen-AR Signaling to Transactivate Genes and Promote Cell Proliferation in Prostate Cancer Cells

Androgen/androgen receptor (AR) signaling drives both the normal prostate development and prostatic carcinogenesis, and patients with advanced prostate cancer often develop resistance to androgen deprivation therapy. The transcription factor Krüppel-like factor 5 (KLF5) also regulates both normal an...

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Detalles Bibliográficos
Autores principales: Li, Juan, Zhang, Baotong, Liu, Mingcheng, Fu, Xing, Ci, Xinpei, A, Jun, Fu, Changying, Dong, Ge, Wu, Rui, Zhang, Zhiqian, Fu, Liya, Dong, Jin-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140031/
https://www.ncbi.nlm.nih.gov/pubmed/32245249
http://dx.doi.org/10.3390/cancers12030748