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Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor

Despite the pivotal role of natural killer (NK) cells in defenses against tumors, their exploitation in cancer treatment is still limited due to their reduced ability to reaching tumor sites and the inhibitory effects of tumor microenvironment (TME) on their function. In this study, we have characte...

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Detalles Bibliográficos
Autores principales: Di Pace, Anna Laura, Tumino, Nicola, Besi, Francesca, Alicata, Claudia, Conti, Libenzio Adrian, Munari, Enrico, Maggi, Enrico, Vacca, Paola, Moretta, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140072/
https://www.ncbi.nlm.nih.gov/pubmed/32178479
http://dx.doi.org/10.3390/cancers12030661