Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface

Down regulation of the major histocompatibility class (MHC) I pathway plays an important role in tumour development, and can be achieved by suppression of HLA expression or mutations in the MHC peptide-binding pocket. The peptide-loading complex (PLC) loads peptides on the MHC-I molecule in a dynami...

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Detalles Bibliográficos
Autores principales: Padariya, Monikaben, Kalathiya, Umesh, Houston, Douglas R., Alfaro, Javier Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140079/
https://www.ncbi.nlm.nih.gov/pubmed/32244998
http://dx.doi.org/10.3390/cancers12030737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140079/
https://www.ncbi.nlm.nih.gov/pubmed/32244998
http://dx.doi.org/10.3390/cancers12030737

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