Cargando…

A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes

Matched-targeted and immune checkpoint therapies have improved survival in cancer patients, but tumor heterogeneity contributes to drug resistance. Our study categorized gene mutations from next generation sequencing (NGS) into three core processes. This annotation helps decipher complex biologic in...

Descripción completa

Detalles Bibliográficos
Autores principales: Larson, Kristian, Kannaiyan, Radhamani, Pandey, Ritu, Chen, Yuliang, Babiker, Hani M., Mahadevan, Daruka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140098/
https://www.ncbi.nlm.nih.gov/pubmed/32188081
http://dx.doi.org/10.3390/cancers12030701