ATM-Deficient Cancers Provide New Opportunities for Precision Oncology

Poly-ADP ribose polymerase (PARP) inhibitors are currently used in the treatment of several cancers carrying mutations in the breast and ovarian cancer susceptibility genes BRCA1 and BRCA2, with many more potential applications under study and in clinical trials. Here, we discuss the potential for e...

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Detalles Bibliográficos
Autores principales: Jette, Nicholas R., Kumar, Mehul, Radhamani, Suraj, Arthur, Greydon, Goutam, Siddhartha, Yip, Steven, Kolinsky, Michael, Williams, Gareth J., Bose, Pinaki, Lees-Miller, Susan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140103/
https://www.ncbi.nlm.nih.gov/pubmed/32183301
http://dx.doi.org/10.3390/cancers12030687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140103/
https://www.ncbi.nlm.nih.gov/pubmed/32183301
http://dx.doi.org/10.3390/cancers12030687

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