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Aurora Kinase A-YBX1 Synergy Fuels Aggressive Oncogenic Phenotypes and Chemoresistance in Castration-Resistant Prostate Cancer

Multifunctional protein YBX1 upregulation promotes castration-resistant prostate cancer (CRPC). However, YBX1 protein abundance, but not its DNA status or mRNA levels, predicts CRPC recurrence, although the mechanism remains unknown. Similarly, the mechanism by which YBX1 regulates androgen receptor...

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Detalles Bibliográficos
Autores principales: Nikhil, Kumar, Raza, Asif, Haymour, Hanan S., Flueckiger, Benjamin V., Chu, Jiachong, Shah, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140108/
https://www.ncbi.nlm.nih.gov/pubmed/32178290
http://dx.doi.org/10.3390/cancers12030660