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Aurora Kinase A-YBX1 Synergy Fuels Aggressive Oncogenic Phenotypes and Chemoresistance in Castration-Resistant Prostate Cancer
Multifunctional protein YBX1 upregulation promotes castration-resistant prostate cancer (CRPC). However, YBX1 protein abundance, but not its DNA status or mRNA levels, predicts CRPC recurrence, although the mechanism remains unknown. Similarly, the mechanism by which YBX1 regulates androgen receptor...
Autores principales: | Nikhil, Kumar, Raza, Asif, Haymour, Hanan S., Flueckiger, Benjamin V., Chu, Jiachong, Shah, Kavita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140108/ https://www.ncbi.nlm.nih.gov/pubmed/32178290 http://dx.doi.org/10.3390/cancers12030660 |
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