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Oxaliplatin-Induced DHX9 Phosphorylation Promotes Oncogenic Circular RNA CCDC66 Expression and Development of Chemoresistance

Circular RNA (circRNA), generated through backsplicing in which the downstream splice donor joins the upstream splice acceptor, is a novel class of RNA molecules. Our previous study found that a novel oncogenic circRNA—consisting exon 8–10 of CCDC66—is aberrantly expressed in colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Lin, Ya-Chi, Yu, Ya-Shan, Lin, Hui-Hsuan, Hsiao, Kuei-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140115/
https://www.ncbi.nlm.nih.gov/pubmed/32187976
http://dx.doi.org/10.3390/cancers12030697