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Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

BACKGROUND: β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron homeostasis,...

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Detalles Bibliográficos
Autores principales: Zarghamian, Parinaz, Azarkeivan, Azita, Arabkhazaeli, Ali, Mardani, Ahmad, Shahabi, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140315/
https://www.ncbi.nlm.nih.gov/pubmed/32268883
http://dx.doi.org/10.1186/s12881-020-01011-3