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Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy
BACKGROUND: β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron homeostasis,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140315/ https://www.ncbi.nlm.nih.gov/pubmed/32268883 http://dx.doi.org/10.1186/s12881-020-01011-3 |