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Variation in base composition underlies functional and evolutionary divergence in non-LTR retrotransposons

BACKGROUND: Non-LTR retrotransposons often exhibit base composition that is markedly different from the nucleotide content of their host’s gene. For instance, the mammalian L1 element is AT-rich with a strong A bias on the positive strand, which results in a reduced transcription. It is plausible th...

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Detalles Bibliográficos
Autores principales: Ruggiero, Robert P., Boissinot, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140322/
https://www.ncbi.nlm.nih.gov/pubmed/32280379
http://dx.doi.org/10.1186/s13100-020-00209-9