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Hippocampal microglial activation triggers a neurotoxic-specific astrocyte response and mediates etomidate-induced long-term synaptic inhibition

BACKGROUND: Accumulating evidence has highlighted the importance of microglial and astrocyte responses in the pathological development of postoperative cognitive dysfunction (POCD). However, the mechanisms involved are not well understood. METHODS: A perioperative neurocognitive disorders (PND) mous...

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Detalles Bibliográficos
Autores principales: Li, Dongliang, Chen, Mingming, Meng, Tao, Fei, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140340/
https://www.ncbi.nlm.nih.gov/pubmed/32264970
http://dx.doi.org/10.1186/s12974-020-01799-0