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Methylation-driven model for analysis of dinucleotide evolution in genomes

BACKGROUND: CpGs, the major methylation sites in vertebrate genomes, exhibit a high mutation rate from the methylated form of CpG to TpG/CpA and, therefore, influence the evolution of genome composition. However, the quantitative effects of CpG to TpG/CpA mutations on the evolution of genome composi...

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Detalles Bibliográficos
Autores principales: Sun, Jian-Hong, Ai, Shi-Meng, Liu, Shu-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140373/
https://www.ncbi.nlm.nih.gov/pubmed/32264909
http://dx.doi.org/10.1186/s12976-020-00122-x