Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies

The human 80S ribosome is the cellular nucleoprotein nanomachine in charge of protein synthesis that is profoundly affected during cancer transformation by oncogenic proteins and provides cancerous proliferating cells with proteins and therefore biomass. Indeed, cancer is associated with an increase...

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Detalles Bibliográficos
Autores principales: Gilles, Arnaud, Frechin, Léo, Natchiar, Kundhavai, Biondani, Giulia, von Loeffelholz, Ottilie, Holvec, Samuel, Malaval, Julie-Lisa, Winum, Jean-Yves, Klaholz, Bruno P., Peyron, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140421/
https://www.ncbi.nlm.nih.gov/pubmed/32151059
http://dx.doi.org/10.3390/cells9030629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140421/
https://www.ncbi.nlm.nih.gov/pubmed/32151059
http://dx.doi.org/10.3390/cells9030629

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