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A Unique GSK-3β inhibitor B10 Has a Direct Effect on Aβ, Targets Tau and Metal Dyshomeostasis, and Promotes Neuronal Neurite Outgrowth

Due to the complicated pathogenesis of Alzheimer’s disease (AD), the development of multitargeted agents to simultaneously interfere with multiple pathological processes of AD is a potential choice. Glycogen synthase kinase-3β (GSK-3β) plays a vital role in the AD pathological process. In this study...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-Long, Yan, Ning, Cui, Ying-Jie, Liu, Zhao-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140427/
https://www.ncbi.nlm.nih.gov/pubmed/32155989
http://dx.doi.org/10.3390/cells9030649