Cargando…
A Unique GSK-3β inhibitor B10 Has a Direct Effect on Aβ, Targets Tau and Metal Dyshomeostasis, and Promotes Neuronal Neurite Outgrowth
Due to the complicated pathogenesis of Alzheimer’s disease (AD), the development of multitargeted agents to simultaneously interfere with multiple pathological processes of AD is a potential choice. Glycogen synthase kinase-3β (GSK-3β) plays a vital role in the AD pathological process. In this study...
Autores principales: | Shi, Xiao-Long, Yan, Ning, Cui, Ying-Jie, Liu, Zhao-Peng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140427/ https://www.ncbi.nlm.nih.gov/pubmed/32155989 http://dx.doi.org/10.3390/cells9030649 |
Ejemplares similares
-
Slit2 Inactivates GSK3β to Signal Neurite Outgrowth Inhibition
por: Byun, Justin, et al.
Publicado: (2012) -
β-Hydroxy-β-Methylbutyrate (HMB) Promotes Neurite Outgrowth in Neuro2a Cells
por: Salto, Rafael, et al.
Publicado: (2015) -
Integrin α5β1 expression on dopaminergic neurons is involved in dopaminergic neurite outgrowth on striatal neurons
por: Izumi, Yasuhiko, et al.
Publicado: (2017) -
WNK1/HSN2 mediates neurite outgrowth and differentiation via a OSR1/GSK3β-LHX8 pathway
por: Shimizu, Masahiro, et al.
Publicado: (2022) -
The regulation of mitochondrial dynamics in neurite outgrowth by retinoic acid receptor β signaling
por: Trigo, Diogo, et al.
Publicado: (2019)