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Silencing of Euchromatic Transposable Elements as a Consequence of Nuclear Lamina Dysfunction

Transposable elements (TEs) are mobile genomic sequences that are normally repressed to avoid proliferation and genome instability. Gene silencing mechanisms repress TEs by RNA degradation or heterochromatin formation. Heterochromatin maintenance is therefore important to keep TEs silent. Loss of he...

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Detalles Bibliográficos
Autores principales: Cavaliere, Valeria, Lattanzi, Giovanna, Andrenacci, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140440/
https://www.ncbi.nlm.nih.gov/pubmed/32151001
http://dx.doi.org/10.3390/cells9030625