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The Role of MYC and PP2A in the Initiation and Progression of Myeloid Leukemias

The MYC transcription factor is one of the best characterized PP2A substrates. Deregulation of the MYC oncogene, along with inactivation of PP2A, are two frequent events in cancer. Both proteins are essential regulators of cell proliferation, apoptosis, and differentiation, and they, directly and in...

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Detalles Bibliográficos
Autores principales: Pippa, Raffaella, Odero, Maria D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140463/
https://www.ncbi.nlm.nih.gov/pubmed/32110991
http://dx.doi.org/10.3390/cells9030544