ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma

The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug. The ATP Binding Cassette transporter A1 (ABCA1) effluxes isopentenyl pyrophosph...

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Detalles Bibliográficos
Autores principales: Belisario, Dimas Carolina, Akman, Muhlis, Godel, Martina, Campani, Virginia, Patrizio, Maria Pia, Scotti, Lorena, Hattinger, Claudia Maria, De Rosa, Giuseppe, Donadelli, Massimo, Serra, Massimo, Kopecka, Joanna, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140509/
https://www.ncbi.nlm.nih.gov/pubmed/32155954
http://dx.doi.org/10.3390/cells9030647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140509/
https://www.ncbi.nlm.nih.gov/pubmed/32155954
http://dx.doi.org/10.3390/cells9030647

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