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ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma
The ATP Binding Cassette transporter B1 (ABCB1) induces chemoresistance in osteosarcoma, because it effluxes doxorubicin, reducing the intracellular accumulation, toxicity, and immunogenic cell death induced by the drug. The ATP Binding Cassette transporter A1 (ABCA1) effluxes isopentenyl pyrophosph...
Autores principales: | Belisario, Dimas Carolina, Akman, Muhlis, Godel, Martina, Campani, Virginia, Patrizio, Maria Pia, Scotti, Lorena, Hattinger, Claudia Maria, De Rosa, Giuseppe, Donadelli, Massimo, Serra, Massimo, Kopecka, Joanna, Riganti, Chiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140509/ https://www.ncbi.nlm.nih.gov/pubmed/32155954 http://dx.doi.org/10.3390/cells9030647 |
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