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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

ATP-binding cassette (ABC) transporters, such as breast cancer resistance protein (BCRP), are key players in resistance to multiple anti-cancer drugs, leading to cancer treatment failure and cancer-related death. Currently, there are no clinically approved drugs for reversal of cancer drug resistanc...

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Detalles Bibliográficos
Autores principales: Ambjørner, Sophie E. B., Wiese, Michael, Köhler, Sebastian Christoph, Svindt, Joen, Lund, Xamuel Loft, Gajhede, Michael, Saaby, Lasse, Brodin, Birger, Rump, Steffen, Weigt, Henning, Brünner, Nils, Stenvang, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140522/
https://www.ncbi.nlm.nih.gov/pubmed/32143347
http://dx.doi.org/10.3390/cells9030613