Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes

Vav1 works both as a catalytic Rho GTPase activator and an adaptor molecule. These functions, which are critical for T cell development and antigenic responses, are tyrosine phosphorylation-dependent. However, it is not known whether other posttranslational modifications can contribute to the regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Fdez, Sonia, Fernández-Nevado, Lucía, Lorenzo-Martín, L. Francisco, Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140538/
https://www.ncbi.nlm.nih.gov/pubmed/32143292
http://dx.doi.org/10.3390/cells9030609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140538/
https://www.ncbi.nlm.nih.gov/pubmed/32143292
http://dx.doi.org/10.3390/cells9030609

Ejemplares similares