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Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes
Vav1 works both as a catalytic Rho GTPase activator and an adaptor molecule. These functions, which are critical for T cell development and antigenic responses, are tyrosine phosphorylation-dependent. However, it is not known whether other posttranslational modifications can contribute to the regula...
Autores principales: | Rodríguez-Fdez, Sonia, Fernández-Nevado, Lucía, Lorenzo-Martín, L. Francisco, Bustelo, Xosé R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140538/ https://www.ncbi.nlm.nih.gov/pubmed/32143292 http://dx.doi.org/10.3390/cells9030609 |
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