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GSK3β: A Master Player in Depressive Disorder Pathogenesis and Treatment Responsiveness
Glycogen synthase kinase 3β (GSK3β), originally described as a negative regulator of glycogen synthesis, is a molecular hub linking numerous signaling pathways in a cell. Specific GSK3β inhibitors have anti-depressant effects and reduce depressive-like behavior in animal models of depression. Theref...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140610/ https://www.ncbi.nlm.nih.gov/pubmed/32188010 http://dx.doi.org/10.3390/cells9030727 |