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GSK3β: A Master Player in Depressive Disorder Pathogenesis and Treatment Responsiveness

Glycogen synthase kinase 3β (GSK3β), originally described as a negative regulator of glycogen synthesis, is a molecular hub linking numerous signaling pathways in a cell. Specific GSK3β inhibitors have anti-depressant effects and reduce depressive-like behavior in animal models of depression. Theref...

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Detalles Bibliográficos
Autores principales: Duda, Przemysław, Hajka, Daria, Wójcicka, Olga, Rakus, Dariusz, Gizak, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140610/
https://www.ncbi.nlm.nih.gov/pubmed/32188010
http://dx.doi.org/10.3390/cells9030727