The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Autophagy is an important innate immune defense mechanism that controls Mycobacterium tuberculosis (Mtb) growth inside macrophages. Autophagy machinery targets Mtb-containing phagosomes via xenophagy after damage to the phagosomal membrane due to the Type VII secretion system Esx-1 or via LC3-associ...

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Detalles Bibliográficos
Autores principales: Bah, Aïcha, Sanicas, Merlin, Nigou, Jérôme, Guilhot, Christophe, Astarie-Dequeker, Catherine, Vergne, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140614/
https://www.ncbi.nlm.nih.gov/pubmed/32182946
http://dx.doi.org/10.3390/cells9030666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140614/
https://www.ncbi.nlm.nih.gov/pubmed/32182946
http://dx.doi.org/10.3390/cells9030666

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