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Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation

Diabetic nephropathy, a devastating consequence of diabetes mellitus, is characterized by the accumulation of extracellular matrix (ECM) that disrupts the kidney’s filtration apparatus. Elevated glucose levels increase the deposition of a fibronectin (FN) matrix by mesangial cells, the primary matri...

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Detalles Bibliográficos
Autores principales: Vega, Maria E., Kastberger, Birgit, Wehrle-Haller, Bernhard, Schwarzbauer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140634/
https://www.ncbi.nlm.nih.gov/pubmed/32182705
http://dx.doi.org/10.3390/cells9030655